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eBook GPI Membrane Anchors download
Science
Author: M. Lucia Cardoso De Almeida
ISBN: 0121593908
Subcategory: Biological Sciences
Pages 320 pages
Publisher Academic Press (June 28, 1992)
Language English
Category: Science
Rating: 4.9
Votes: 578
ePUB size: 1621 kb
FB2 size: 1880 kb
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eBook GPI Membrane Anchors download

by M. Lucia Cardoso De Almeida


Semantic Scholar profile for M L Cardoso de Almeida, with fewer than 50 highly influential citations.

Semantic Scholar profile for M L Cardoso de Almeida, with fewer than 50 highly influential citations.

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The book examines the GPI structure and its originality as an anchoring device, its ubiquitous distribution, the main steps of its biosynthetic pathway, and the elegant means by which a protein signals for GPI attachment. It also presents evidence for the uniqueness of GPI as a tag in intracellular traffic and as a mediator of transmembrane signaling.

inositol (GPI) membrane anchors are ubiquitous among the eukaryotes. In most organisms, the pathway of GPI biosynthesis involves inositol acylation and inositol deacylation as discrete steps at the beginning and end of the pathway, respectively

inositol (GPI) membrane anchors are ubiquitous among the eukaryotes. In most organisms, the pathway of GPI biosynthesis involves inositol acylation and inositol deacylation as discrete steps at the beginning and end of the pathway, respectively. The bloodstream form of the protozoan parasite Trypanosoma brucei is unusual in that these reactions occur on multiple GPI intermediates and that it can express side chains of up to six galactose residues on its mature GPI anchors.

GPI Membrane Anchors by Almeida, M and Publisher Academic Press. Canadian customers may purchase from our stores in Canada or the US. Canada. Save up to 80% by choosing the eTextbook option for ISBN: 9780121593902, 9780323156097, 0323156096. The print version of this textbook is ISBN: 9780121593902, 0121593908.

The gene for the second membrane anchor peptide in yeast was obtained by isolating the Sdh4 peptide, determining an amino-terminal sequence to obtain degenerate, gene-specific oligonucleotide primers, and adapting a reverse transcriptase (RT)-PCR protocol. Gene disruption resulted in a mutant phenotype that is characterized by greatly reduced levels of SDH activity, and c reductase activity, as well as the inability to grow on a nonfermentable carbon source (glycerol) (96). View chapter Purchase book. Membrane Structure and Dynamics. In Cell Biology (Third.

linositol (GPI) membrane anchors are ubiquitous in the eukaryotic kingdom (Ferguson and Williams, 1988; Low, 1989 . A book on the subject of GPI anchors was recently published (Cardoso de Almeida, 1992).

linositol (GPI) membrane anchors are ubiquitous in the eukaryotic kingdom (Ferguson and Williams, 1988; Low, 1989; Cross, 1990; Ferguson, 1991, 1992a). Their primary function is to afford the stable association of certain glycoproteins with the exoplasmic face of the plasma membrane, or the topologically equivalent luminal face of secretory granules.

linositol (GPI) membrane anchors are present in organisms at most stages of eukaryotic evolution, including protozoa, yeast, slime moulds, invertebrates and vertebrates, and are found on a diverse range of proteins. They are primarily responsible for the anchoring of cell-surface proteins in the plasma membrane (or in some cases to the topologically equivalent lumenal surface of secretory vesicles) and may be considered as an alternative to the hydrophobic transmembrane polypeptide anchor of type-1 integral membrane proteins (Fig.

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This book focuses on GPI-anchored molecules in biomembranes, their organization, biosynthesis, function as receptors and use as engineered molecules

This book focuses on GPI-anchored molecules in biomembranes, their organization, biosynthesis, function as receptors and use as engineered molecules. An extensive chapter is also devoted to discussing the structures of microbial GPI-anchored molecules and bioactivities on mammalian host cell membranes. Download (pdf, . 6 Mb) Donate Read. Epub FB2 mobi txt RTF.

This collection of papers reviews current research in a new topic in cell biology - cell signalling. Among the topics discussed are recent experimental results; and views into structural evolution. The book is aimed at research-level cell biologists, molecular biologists, and biochemists.