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eBook Modeling in Systems Biology: The Petri Net Approach (Computational Biology) download
Science
Author: Ina Koch,Wolfgang Reisig,Falk Schreiber
ISBN: 1849964734
Subcategory: Biological Sciences
Pages 364 pages
Publisher Springer; 2011 edition (October 25, 2010)
Language English
Category: Science
Rating: 4.7
Votes: 362
ePUB size: 1761 kb
FB2 size: 1268 kb
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eBook Modeling in Systems Biology: The Petri Net Approach (Computational Biology) download

by Ina Koch,Wolfgang Reisig,Falk Schreiber


Modeling in Systems Biology: The Petri Net Approach (Computational Biology). Ina Koch, Wolfgang Reisig, Falk Schreiber.

Modeling in Systems Biology: The Petri Net Approach (Computational Biology). Download (pdf, . 3 Mb) Donate Read.

The Petri Net Approach. Dr. Ina Koch is a Professor and holds the Chair of Bioinformatics at the Johann Wolfgang Goethe-University Frankfurt am Main, Germany.

Petri net Systems biology T-invariant MCT-set T-cluster Citrate cycle. Modeling in Systems Biology: The Petri Net Approach, pp. 153–178. Springer, Berlin (2011) (Comp. Communicated by Dr. Wolfgang Reisig. I also would like to thank Jörg Ackermann, Falk Schreiber, Björn Junker, Andrea Sackmann, Eva Grafahrend-Belau, Astrid Speer and Stefanie Grunwald for fruitful collaboration. Additionally, many thanks to Michael Rücker for the professional translation and careful reading of this article. 2. Ackermann, . et al.

The emerging, multi-disciplinary field of systems biology is devoted to the study .

The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques.

The Petri net approach offers not only the basic tools that Carl Adam Petri .

The Petri net approach offers not only the basic tools that Carl Adam Petri is said to have invented as a schoolboy, but in addition many extensions and expansions of those ideas, so that it becomes possible to combine quite a variety of modular elements (discrete, quasi-continuous, stochastic, spatially expanded, topologically involved, time-delayed, dimensionally separated, et. into one model. For about 15 years, Petri net models of biochemical systems have been successfully developed, simulated, and analyzed

Dr. Wolfgang Reisig is a Professor and holds the Chair in the Theory of Programming at the Humboldt University of Berlin, Germany.

Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments.

Computational Biology. Koch, Ina, Reisig, Wolfgang, Schreiber, Falk. Assembled Product Dimensions (L x W x H). 0 x . 0 Inches.

The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive overview of cutting-edge research in applications of Petri nets in systems biology, with contributions from an international selection of experts. Those unfamiliar with the field are also provided with a general introduction to systems biology, the foundations of biochemistry, and the basics of Petri net theory. Further chapters address Petri net modeling techniques for building and analyzing biological models, as well as network prediction approaches, before reviewing the applications to networks of different biological classification. Topics and features: investigates the modular, qualitative modeling of regulatory networks using Petri nets, and examines an Hybrid Functional Petri net simulation case study; contains a glossary of the concepts and notation used in the book, in addition to exercises at the end of each chapter; covers the topological analysis of metabolic and regulatory networks, the analysis of models of signaling networks, and the prediction of network structure; provides a biological case study on the conversion of logical networks into Petri nets; discusses discrete modeling, stochastic modeling, fuzzy modeling, dynamic pathway modeling, genetic regulatory network modeling, and quantitative analysis techniques; includes a Foreword by Professor Jens Reich, Professor of Bioinformatics at Humboldt University and Max Delbrück Center for Molecular Medicine in Berlin. This unique guide to the modeling of biochemical systems using Petri net concepts will be of real utility to researchers and students of computational biology, systems biology, bioinformatics, computer science, and biochemistry.