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eBook DNA Vaccination/Genetic Vaccination (Current Topics in Microbiology and Immunology) download
Medical Books
Author: Hilary Koprowski,David B. Weiner
ISBN: 3540633928
Subcategory: Medicine
Pages 198 pages
Publisher Springer; 1 edition (December 23, 1997)
Language English
Category: Medical Books
Rating: 4.2
Votes: 794
ePUB size: 1307 kb
FB2 size: 1343 kb
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eBook DNA Vaccination/Genetic Vaccination (Current Topics in Microbiology and Immunology) download

by Hilary Koprowski,David B. Weiner


Current Topics in Microbiology and Immunology. Genetic, DNA immunization represents a novel approach to vaccine and immune therapeutic development. Current Topics in Microbiology and Immunology.

Current Topics in Microbiology and Immunology. The direct injec­ tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene­ delivered antigen.

DNA vaccination/genetic vaccination. February 1998 · Current topics in microbiology and immunology. What type of file do you want? RIS.

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Genetic, DNA immunization represents a novel approach to vaccine and immune therapeutic development

Genetic, DNA immunization represents a novel approach to vaccine and immune therapeutic development.

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Weiner HILARY KOPROWSKI, .

With 31 Figures and 14 Tables, Springer. HILARY KOPROWSKI, . Professor Thomas Jefferson University Department of Microbiology and Immunology Center for Neurobiology Rm. M-85, Jefferson Alumni Hall 1020 Locust Street Philadelphia, PA 19197-6799 USA DAVID B. WEINER, P. Associate Professor University of Pennsylvania School of Medicine Hospital of the University of Pennsylvania Department of Pathology and Laboratory Medicine 500 Stellar-Chance Bldg.

Bibliographic Details. Publication Date: 2011.

DNA Vaccination/Genetic – 14 December 2011.

Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec­ tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene­ delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against both specific infectious diseases and cancers is likely to have dramatic consequences for the develop­ ment of a new generation of experimental vaccines and immune therapies. This technology has the potential to enable the pro­ duction of vaccines and immune-based therapies that are not only effective immunologically but are accessible to the entire world (rather than just to the most developed nations). Vaccine Development Vaccination against pathogenic microorganisms represents one of the most important advances in the history of medicine. Vaccines, including those against polio, measles, mumps, rubella, hepatitis A, hepatitis B, pertussis and other diseases, have dramatically improved and protected more human lives than any other avenue of modern medicine. The vaccine against smallpox, for example, has been so successful that it is now widely believed that this malicious killer, responsible for more deaths in the twentieth century than World Wars I and II combined, has been removed from the face of the earth.